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What is AST ALT ratio? The AST/ALT ratio (or alt/ast ratio) is AST ÷ ALT—used to help distinguish liver disease types. Use this free AST/ALT ratio calculator—an AST to ALT ratio calculator and ALT to AST ratio calculator—to calculate AST ALT ratio from your lab values. Works as an AST ALT calculator, liver enzyme ratio calculator, and SGOT SGPT ratio calculator (AST = SGOT, ALT = SGPT). Get AST ALT ratio normal range and interpretation. No sign-up.
Last updated: February 2, 2026
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Normal range: 10-40 U/L (may vary by lab)
Normal range: 7-56 U/L (may vary by lab)
AST/ALT Ratio
1.25
Balanced ratio (AST/ALT 1-2)
Severity Assessment:
Moderate Liver Injury
Clinical Interpretation:
May indicate early alcoholic liver disease or chronic hepatitis
AST Normal:
10-40 U/L
ALT Normal:
7-56 U/L
Clinical Considerations:
Important Medical Notice:
Use this free AST/ALT ratio calculator as an AST to ALT ratio calculator and ALT to AST ratio calculator (same ratio: AST ÷ ALT). Calculate AST ALT ratio from your lab values—works as alt/ast ratio calculator, ast and alt ratio calculator, liver enzyme ratio calculator, and SGOT SGPT ratio calculator (AST = SGOT, ALT = SGPT). Get AST ALT ratio normal range and interpretation.
To calculate ast alt ratio: divide AST by ALT. Formula: ratio = AST ÷ ALT. Enter your AST and ALT values in the calculator above to get the ratio and clinical interpretation. This ast to alt ratio calculator and alt to ast ratio calculator (ratio of ast to alt = ratio of alt to ast inverted; we show AST/ALT) works as an ast alt calculator and alt ast ratio calculator—same sgot sgpt ratio calculator (SGOT = AST, SGPT = ALT).
AST ALT ratio normal range: Ratio 1.0–2.0 is often balanced. <1 suggests NAFLD or viral hepatitis; ≥2 suggests alcoholic liver disease. Normal ast alt ratio and normal ast/alt ratio depend on context—when enzymes are normal, ratio is less critical. Use this tool to see your ast alt ratio chart interpretation (ratio <1, 1–2, ≥2) and ast/alt ratio interpretation. What is a normal ast alt ratio? Typically 1.0–2.0; interpretation depends on absolute levels and clinical context.
Typical range
0.3 - 0.9
Suggests NAFLD, viral hepatitis, or acute hepatitis
Typical range
1.0 - 2.0
May indicate early alcoholic liver disease or chronic hepatitis
Typical range
2.0 - 6.0+
Highly suggestive of alcoholic liver disease or cirrhosis
Normal values
10-40 U/L
Found in liver, heart, muscle, kidney, and red blood cells
Normal values
7-56 U/L
More specific for liver - primarily found in hepatocytes
Key benefit
Disease Differentiation
Helps distinguish alcoholic from non-alcoholic liver disease
AST: 35 U/L, ALT: 28 U/L:
AST/ALT Ratio
1.25
Pattern
Balanced
Severity
Normal
Our AST/ALT ratio calculator uses established clinical guidelines to interpret liver enzyme levels. The ratio provides valuable diagnostic information about liver disease etiology and helps differentiate between alcoholic and non-alcoholic causes of hepatocellular injury.
The ratio is more diagnostically useful than either enzyme alone. In alcoholic liver disease, mitochondrial AST is released preferentially, while ALT is more affected in viral and metabolic liver diseases. The ratio pattern helps narrow differential diagnosis.
Different AST/ALT ratios suggest specific liver conditions:
Explore more liver assessment tools like our Child-Pugh score calculator and blood pressure MAP calculator.
Get Custom Medical CalculatorTypical Ratio
0.3 - 0.8
Enzyme Pattern
ALT > AST
Most common liver disease. ALT typically 2-3x higher than AST. Associated with metabolic syndrome.
Typical Ratio
2.0 - 6.0
Enzyme Pattern
AST >> ALT
Ratio ≥2 is 80% sensitive for alcoholic liver disease. AST rarely exceeds 500 U/L in alcoholic hepatitis.
Typical Ratio
0.5 - 1.0
Enzyme Pattern
ALT ≥ AST
Can have very high transaminases (>1000 U/L). ALT typically exceeds AST in acute viral hepatitis.
Typical Ratio
1.0 - 4.0
Enzyme Pattern
Variable
Ratio increases as cirrhosis progresses. Both enzymes may be only mildly elevated in advanced disease.
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